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NELLA TECNOLOGIA1 PIÙ AVANZATA




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Confezione multidose
Senza Purite 2
Compatibile con
le lenti a contatto 2
Dura 3 mesi
dall’apertura 2





Gli studi elencati si riferiscono ad Optive Fusion, avente medesima composizione di Optive Advance ad eccezione della presenza del conservante Purite.

BIBLIOGRAFIA
1) Allergan Data on File - MDPF Container Closure System
2) Optive Advance, Istruzioni per l’uso
3) Aragona P, et al, . Long term treatment with sodium hyaluronate containing artificial tears reduces ocular surface damage in patients with dry eye. Br J Ophthalmol 2002;86[2]:181-84 4
4) Data on file Allergan, Inc. Protocol 10078X-001
5) Garret et al, Carboxymethylcellulose Binds to Human Corneal Epithelial Cells and Is a Modulator of Corneal Epithelial Wound Healing, Investigative Ophthalmology & Visual Science, April 2007, Vol. 48, No. 4
6) Baudouin C, et al, Role of Hyperosmolarity in the Pathogenesis and Management of Dry Eye Disease: Proceedings of the OCEAN Group Meeting, THE OCULAR SURFACE / OCTOBER 2013, VOL. 11 NO. 4 / www.theocularsurface.com
7) Aragona et al, Physicochemical Properties of Hyaluronic Acid–Based Lubricant Eye Drops, Trans Vis SciTech. 2019;8(6):2
8) Stepto R et al Dispensity in polymer science. Pure applied Chemistry, 2009, 82(2):351-353
9) Kadajji V and Betageri G. Water Soluble Polymers for Pharmaceutical Applications Polymers 2011;3:1072-2009 10) She et al, Evaluation of a Novel Artificial Tear in the Prevention and Treatment of Dry Eye in an Animal Model, JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS Volume 31, Number 9, 2015 DOI: 10.1089/jop.2015.0042
11) Orbia et al, Comabination of hyaluronic acid, carmellose and osmoprotectans for the treatment of dry eye, Clinical Ophthalmology 2018:12 453–461
12) Deng et al, Osmoprotectants suppress the production and activity of matrix metalloproteinases induced by hyperosmolarity in primary human corneal epithelial cells, Mos Vis, 2014